I recently got a Huion H420 drawing tablet.
So I booted it up, installed the driver and started to test it out.
But what I found surprised me, when I was testing on Sketch.io, my pen moved in the opposite direction of my hand, don't know why.
11 Answer
Check in the driver software is there a setting for the side where you want the buttons reside. That can be named left handed-right handed selection. Change the selected position or rotate the tablet.